Felipe Fregni Selected Research

3- (3,5- dichlorophenyl)- 1- methyl- 2,5- pyrrolidinedione (DPMS)

1/2023	Primary somatosensory cortex and periaqueductal gray functional connectivity as a marker of the dysfunction of the descending pain modulatory system in fibromyalgia.
11/2022	Functional connectivity response to acute pain assessed by fNIRS is associated with BDNF genotype in fibromyalgia: an exploratory study.
1/2022	The effect of home-based transcranial direct current stimulation in cognitive performance in fibromyalgia: A randomized, double-blind sham-controlled trial.
1/2022	Association between descending pain modulatory system and cognitive impairment in fibromyalgia: A cross-sectional exploratory study.
1/2022	Hyper-connectivity between the left motor cortex and prefrontal cortex is associated with the severity of dysfunction of the descending pain modulatory system in fibromyalgia.
5/2021	Mapping of predictors of the disengagement of the descending inhibitory pain modulation system in fibromyalgia: an exploratory study.
10/2020	Brain-Derived Neurotrophic Factor Modulates the Effect of Sex on the Descending Pain Modulatory System in Healthy Volunteers.
1/2020	The Hypnotic Analgesia Suggestion Mitigated the Effect of the Transcranial Direct Current Stimulation on the Descending Pain Modulatory System: A Proof of Concept Study.
1/2019	Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study.
1/2019	Potency of descending pain modulatory system is linked with peripheral sensory dysfunction in fibromyalgia: An exploratory study.

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Felipe Fregni Research Topics

Disease

132	Pain (Aches) 04/2024 - 05/2006
58	Stroke (Strokes) 03/2024 - 09/2005
48	Chronic Pain 03/2024 - 04/2006
35	Fibromyalgia (Fibrositis) 02/2024 - 12/2006
22	Neuralgia (Stump Neuralgia) 04/2024 - 10/2008
16	Major Depressive Disorder (Major Depressive Disorders) 10/2023 - 08/2008
15	Spinal Cord Injuries (Spinal Cord Injury) 01/2021 - 05/2006
14	Phantom Limb (Phantom Limbs) 03/2024 - 08/2013
13	Knee Osteoarthritis 12/2023 - 10/2008
13	Epilepsy (Aura) 01/2021 - 09/2005
13	Parkinson Disease (Parkinson's Disease) 01/2021 - 09/2005
9	Myofascial Pain Syndromes (Myofascial Pain Syndrome) 01/2020 - 10/2013
9	Cerebral Palsy (Spastic Diplegia) 07/2017 - 07/2007
8	Cognitive Dysfunction 04/2024 - 12/2007
7	Fatigue 10/2023 - 01/2015
7	Hyperalgesia 11/2020 - 10/2008
6	Osteoarthritis 01/2023 - 10/2008
6	Schizophrenia (Dementia Praecox) 01/2021 - 03/2009
6	Seizures (Absence Seizure) 01/2020 - 02/2006
6	Aphasia (Dysphasia) 01/2018 - 05/2004
5	Inflammation (Inflammations) 01/2023 - 01/2011
5	Persistent Vegetative State (Vegetative State) 03/2022 - 05/2017
5	Intractable Pain 01/2021 - 10/2008
5	Nervous System Diseases (Neurological Disorders) 01/2021 - 10/2005
5	Treatment-Resistant Depressive Disorder 01/2021 - 12/2006
5	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020 - 10/2008
5	Tinnitus 01/2017 - 04/2006
5	Visceral Pain 01/2017 - 01/2007
4	Consciousness Disorders 10/2023 - 01/2019
4	Sleepiness 07/2022 - 06/2011
4	Burns 01/2021 - 01/2013
4	Alcoholism (Alcohol Abuse) 01/2021 - 01/2008
4	Depressive Disorder (Melancholia) 01/2021 - 09/2010
4	Drug Resistant Epilepsy 01/2018 - 01/2005
4	Alzheimer Disease (Alzheimer's Disease) 07/2017 - 12/2007
3	Mental Disorders (Mental Disorder) 01/2024 - 01/2021
3	Postoperative Pain 01/2023 - 01/2017
3	Acute Pain 11/2022 - 05/2015
3	COVID-19 11/2022 - 01/2020
3	Pruritus (Itching) 03/2021 - 09/2011
3	Wounds and Injuries (Trauma) 01/2021 - 10/2010
3	Migraine Disorders (Migraine) 01/2021 - 05/2006
3	Low Back Pain (Lumbago) 01/2020 - 01/2016
3	Muscle Spasticity (Spastic) 01/2016 - 11/2014
3	Headache (Headaches) 05/2015 - 06/2011
2	Neoplasms (Cancer) 01/2021 - 01/2019
2	Substance-Related Disorders (Drug Abuse) 01/2021 - 06/2015
2	Cancer Pain 01/2021 - 01/2019
2	Neuroinflammatory Diseases 01/2021 - 01/2020
2	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2019
2	Obesity 01/2020 - 02/2019
2	Paresis (Hemiparesis) 01/2019 - 01/2018
2	Ischemic Stroke 01/2019 - 01/2019
2	Encephalitis (Encephalitis, Rasmussen) 01/2018 - 01/2011
2	Hippocampal Sclerosis 01/2018 - 01/2017
2	Mania (Manias) 01/2017 - 07/2013
2	Spinal Injuries (Spinal Injury) 01/2017 - 07/2016
2	Prader-Willi Syndrome (Syndrome, Prader-Willi) 03/2016 - 05/2009
2	Hyperphagia (Overeating) 03/2016 - 05/2009

Drug/Important Bio-Agent (IBA)

99	salicylhydroxamic acid (SHAM)IBA 02/2024 - 01/2006
32	Analgesics (Analgesic Drugs)IBA 04/2024 - 10/2008
30	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2023 - 12/2008
21	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2011
16	3- (3,5- dichlorophenyl)- 1- methyl- 2,5- pyrrolidinedione (DPMS)IBA 01/2023 - 01/2017
9	Antidepressive Agents (Antidepressants)IBA 04/2024 - 10/2005
7	Opioid Analgesics (Opioids)IBA 04/2024 - 01/2012
5	MelatoninIBA 01/2020 - 01/2013
4	Interleukin-10 (Interleukin 10)IBA 01/2023 - 11/2015
4	ElementsIBA 01/2022 - 04/2006
4	Nerve Growth Factors (Neurotrophins)IBA 01/2021 - 01/2016
4	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020 - 06/2006
4	Therapeutic UsesIBA 04/2017 - 06/2006
3	Lidocaine (Xylocaine)FDA LinkGeneric 04/2024 - 03/2014
3	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2016
3	Pregabalin (Lyrica)FDA Link 04/2022 - 11/2009
3	Hypnotics and Sedatives (Sedatives)IBA 01/2020 - 09/2013
3	Fluoxetine (Prozac)FDA LinkGeneric 01/2019 - 09/2005
3	Sertraline (Zoloft)FDA LinkGeneric 10/2013 - 01/2011
2	CytokinesIBA 01/2023 - 03/2016
2	Proteins (Proteins, Gene)FDA Link 05/2021 - 01/2019
2	EsketamineIBA 01/2021 - 01/2019
2	InterleukinsIBA 11/2020 - 11/2015
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 11/2009

Therapy/Procedure

193	Transcranial Direct Current Stimulation 04/2024 - 09/2005
81	Transcranial Magnetic Stimulation 04/2024 - 05/2004
43	Therapeutics 04/2024 - 09/2008
11	Electrodes (Electrode) 05/2021 - 01/2007
8	Analgesia 01/2023 - 09/2012
7	Vagus Nerve Stimulation 03/2024 - 06/2010
7	Surgical Amputation (Amputations) 02/2024 - 08/2013
7	Aftercare (After-Treatment) 01/2021 - 09/2010
7	Drug Therapy (Chemotherapy) 01/2020 - 10/2013
6	Neurological Rehabilitation 01/2021 - 10/2007
4	Mirror Movement Therapy 01/2023 - 07/2016
3	Neurofeedback 01/2022 - 03/2008
3	Physical Therapy Modalities (Physical Therapy Technique) 01/2021 - 11/2014
3	Deep Brain Stimulation 10/2020 - 06/2010
3	Hypnosis (Mesmerism) 12/2014 - 03/2008
2	Transcutaneous Electric Nerve Stimulation (TENS) 10/2020 - 10/2009
2	Adjuvant Chemotherapy 01/2020 - 01/2019